Alanine Aminotransferase (ALT/SGPT)
Fasting Required: Yes 12 hours

Specimen: Blood

Lab: Quest Diagnostics

Results: 1-2 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Limitations: Trauma to striated muscle, tissue, rhabdomyolysis, polymyositis, and dermatomyositis may produce increased results. Hemolyzed samples may yield elevated results. Some illegal drugs (cocaine, anabolic steroids, ecstasy) may also produce increased results.

Description: Alanine aminotransferase (ALT) is an enzyme found mostly in the cells of the liver and kidney. ALT is normally found inside liver cells but, when the liver is damaged or inflamed, can be released into your bloodstream. Measuring ALT levels is particularly useful in the diagnosis and management of certain liver diseases such as viral hepatitis and cirrhosis. Significant elevations of ALT occur only in diseases of the liver. ALT is often measured in conjunction with AST to determine whether the source of the AST is the liver or the heart. ALT is normally not elevated in cases of myocardial infarction, i.e., a normal ALT, in conjunction with an elevated AST, tends to suggest cardiac disease. However, slight elevations of ALT may occur if an infarct destroys a very large volume of heart muscle.

Alternative Name(s): ALT, Serum Glutamic-Pyruvic Transaminase, SGPT, GPT, Alanine Transaminase