Essential Estrogens-Genova Kit

Note: This is a test kit that will be mailed to you.


Fasting Required: No

Specimen: Urine

Special Instructions: Ship to lab Monday-Thursday only.

Results: 21 Business days
Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Description:
The Essential Estrogens® hormone test provides a focused overview of estrogen balance in both pre- and post-menopausal women. Using a single urine sample, the Essential Estrogens® hormone test evaluates the dynamics of sex steroid metabolism that can profoundly affect a woman´s health throughout her lifetime. The Essential Estrogens® hormone test is designed to assist in the prevention and treatment of estrogen-related symptoms and conditions. This robust urine analysis is ideal for prescribing and monitoring Hormone Replacement Therapy (HRT) and for assessing the risk of estrogen-related diseases, including breast cancer risk, prostate disease, osteoporosis, and auto-immune disease.

Female Hormones and Hormone Testing
Hormones are tremendously complex. During the pre-menopausal years, imbalanced hormones can pose challenges with mood stabilization, conception, and regulations of the menstrual cycle.

Many women entering their 40’s and 50’s experience a range of symptoms from hormonal imbalance, including loss of sex drive, “brain fog”, weight gain, hot flashes, irregular menstrual cycles, vaginal dryness, urinary incontinence, depression and/or changes in sleep patterns.

Essential Estrogens® Hormone Testing and Hormone Replacement Therapy (HRT)

From the onset of ones period through menopause and beyond, proper hormone balance affects many of the issues most important to women: fertility, sex, relationships, and even ones outlook on life. Establishing hormonal baseline measures is essential to determining the need for hormone replacement therapy (HRT) or other means of balancing hormones.

The Essential Estrogens® hormone test measures the following urinary estrogens and estrogen metabolites, and includes an assessment of estrogen methylation, which is a critical step in the protective mechanism of estrogen metabolism.

Estrogens:

1. Estrone 1 (E1)
2. Estradiol (E2)
3. Estriol (E3)

Estrogen Metabolites:

1. 2-Hydroxy-estrone
2. 2-Methoxy-estrone
3. 4-Hydroxy-estrone
4. 4-Methoxy-estrone
5. 16-Alpha-Hydroxy-estrone
6. 2:16 Ratio:
7. 2-Hydroxy-estrone/16-Alpha-Hydroxy-estrone ratio

Estrogen Methylation:

1. 2-Methoxy-estrone/2-Hydroxy-estrone ratio

Estrogens, particularly estrone and estradiol, are well described in literature regarding the health and disease of estrogen sensitive tissues.

Estrogen deficiency:

1. Osteoporosis
2. Amenorrhea
3. Menopausal symptoms

Estrogen excess:

1. Menorrhagia
2. Uterine Fibroids
3. Anxiety/Irritability
4. Breast Cancer

Estrogen metabolites are proven to convey protection (if balanced) or increased risk (if imbalanced) for disease. Estrogen metabolite imbalance results in increased risk of:

1. Breast Cancer
2. Osteoporosis
3. Prostate Cancer

Estrogen methylation is a critical step in the protective mechanism of estrogen metabolism. Methylation is required for the protective effects of 2-hydroxy-estrone, and for the same detoxification of 4-hydroxy-estrone.