Urine Porphyrins 24-hour Urine-Doctor's Data Kit

Note: This is a home collection test kit that will be mailed to you.

Fasting Required: No

Lab: Doctors Data

Specimen: Urine, 24-hour collection

Results: 7-10 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Special Instructions: Do not consume excessive amounts of liquids during the collection period.
If you are taking antibiotics, please finish the course of medication, and then wait 48 hours before starting this collection.
Please refrain from taking non-essential medications 48 hours prior to and during the specimen collection, unless otherwise instructed by your physician. Female patients should not collect urine during a menstrual period.

Description: Abnormal levels of urinary porphyrins, oxidized metabolites of heme biosynthesis, are associated with genetic disorders, metabolic disturbances and diseases, anemias, oxidative stress, and high-level exposure to toxic chemicals or metals. Specific urine porphyrin profiles are associated with high-level exposure to mercury, arsenic, lead and some chemicals and drugs.

Urinary porphyrins are readily excreted in excess when porphyrinogens accumulate as a result of inhibition of specific enzymes in the heme biosynthetic pathway. Heme is required for oxygen binding, transport and utilization, cytochromes, and electron transport in mitochondria. The high rate of production of heme facilitates the use of urinary porphyrins as early and sensitive biomarkers of disorders in heme production, which has long been associated with genetic disorders, metabolic disturbances and diseases, nutritional status, oxidative stress and high-level exposure to toxic chemicals or metals.

Analytes Tested:
Copro I-Copro III ratio
Coproporphyrin I
Coproporphyrin III
Precoproporphyrin Peak I
Precoproporphyrin Peak II
Precoproporphyrin Peak III
Precoproporphyrin Uro Ratio
Total Porphyrins
Total Precoproporphyrin Peak IIII