A-Fetoprotein (AFP), Serum, Tumor Marker
Fasting Required: No

Specimen: Blood

Results: 2-3 Business Days

Description:
The most important application of AFP (Alpha-Fetoprotein) testing in cancer management is for testicular cancer. Although not present in pure seminoma (testis cell tumor), elevated serum AFP is closely associated with nonseminomatous testicular cancer.

Methodology
Immunoassay

Limitations
Patients who have received monoclonal mouse antibodies may have abnormal results. For any patient taking a high dose of biotin, the specimen should be drawn at least eight hours after the last dose.

Clinical Significance
Elevation of serum AFP above values found in healthy individuals occurs in several malignant diseases, most notably nonseminomatous testicular cancer and primary hepatocellular carcinoma. AFP is not recommended as a screening procedure to detect cancer in the general population.

Alternative Name(s)
AFP

Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.