Protein C Activity
Fasting Required: No

Specimen: Blood

Results: Test run Mon, Wed, Fri; Report available in 5-7 Business days

Methodology: Clotting Assay

Description: Protein C is a vitamin K-dependent glycoprotein that is synthesized in the liver. It circulates in an inactive form. It is activated by the thrombin-thrombomodulin complex on endothelial cells. Activated protein C degrades the activated clotting factors Va and VIIIa.

This test aids in the diagnosis of decreased activity of Protein C characterized by recurrent venous thrombosis. Acquired deficiencies associated with Protein C include: Oral anticoagulant therapy, liver disease, vitamin K deficiency, malignancy, consumptive DIC, surgery, trauma, antibodies to Protein C and hepatic immaturity of the newborn.

Alternate Name(s): Protein C Chromogenic, Protein C Functional, Functional Protein C

Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.