Centromere B Antibody
Fasting Required: No

Specimen: Blood

Lab: Quest Diagnostics

Results: 5-7 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Description: Centromere B is an autoantibody, a protein produced by the immune system that mistakenly targets the body's own tissues. The Centromere B Antibody test may be ordered when a person has a positive result on an ANA test and one or more of the symptoms associated with CREST. These symptoms include:

Calcinosis – calcium deposits under the skin
Raynaud phenomenon – episodes of decreased blood flow to fingers and toes, causing them to turn white and blue
Esophageal dysfunction – difficulty swallowing, acid reflux, and heartburn
Sclerodactyly – tight, thick, shiny skin on the hands and fingers
Telangiectasia – red spots on skin due to swollen capillaries