Zonulin (Add-On Only)-Diagnostic Solutions Kit
Coupon Codes not valid for Add-on testing.

Note: This is a home collection test kit that will be mailed to you.


Fasting Required: No

Specimen: Stool

Special Instructions: Ship to lab Monday-Friday only. Specimen MUST be received by the lab within 6 days of collection. If you cannot ship the specimen on the day of collection, please refrigerate the sample. Avoid taking aspirin for 2 days prior to collection. DO NOT discontinue and medications unless directed by your physician.

Results: 5-7 Business Days

Description: Zonulin is a protein secreted by intestinal cells that regulates intercellular tight junctions which are the connections between epithelial cells that make up the gastrointestinal lining. Zonulin increases intestinal permeability in the jejunum and ileum and is considered a biomarker for barrier permeability. Tight junctions can be opened or closed, depending on the physiological need. Zonulin’s role is to open tight junctions in the gut. In the case of enteric infections, high zonulin can “open the floodgates” and flush out bacteria and toxins. Certain gut bacteria and gliadin (the main staple protein from wheat) can activate the zonulin system.

Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.