CytoDx (Cytokine assay, serum)-Diagnostic Solutions Kit

Note: This is a test kit that will be mailed to you. It requires a blood draw. It is your responsibility to arrange the blood draw for your kit and payment of your specimen collection.

Fasting Required: No

Specimen: Blood

Special Instructions: Ship frozen specimen to lab Monday-Thursday only. DO NOT discontinue and medications unless directed by your physician.

Results: 10-12 Business Days

Analytes Included:
Interleukin-1beta (1L-1ß ); Interleukin-2; Interleukin-4; Interleukin-5; Interleukin-6; Interleukin-7; Interleukin-8; Interleukin-10; Interleukin-12; Interleukin-13; Interleukin-15; Interleukin-17; Interleukin-18; Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF); Interferon-gamma IFNy; Tumor Necrosis Factor-alpha (TNF-alpha)

Description: CytoDx is an advanced multiplex immunoassay that provides quantitative measurement of serum levels of 16 cytokines. Multiplex immunoassays represent a significant advance in the assessment of cytokines, owing to the development of high-throughput technologies and enhanced detection capabilities, which enables the cost effective quantification of multiple cytokines from a single serum sample.

Cytokines play critical roles in the development and functioning of the immune system. They also mediate interactions among the immune system, digestive system, nervous system, endocrine system, and metabolism. Cytokines are proteins that are produced by immune cells and many other cell types. They can function in autocrine, paracrine or endocrine fashion as soluble signals among many cell types, including immune cells, fibroblasts, endothelial cells, hepatocytes, adipocytes, nerve cells, and many other cell types.

Imbalances in certain cytokines have been shown to promote chronic inflammation and autoimmunity, and have been linked to a wide range of health conditions and diseases. Most cytokines can be generally characterized as pro-inflammatory or anti-inflammatory, depending on their primary effects on immune responses. Some cytokines, such as IL-6, can serve both pro-inflammatory and anti-inflammatory functions, depending on the specific context. Characterizing cytokines according to their role in promoting inflammation or restraining inflammation, is a very useful way of understanding their general effects.

Because cytokines are involved in many different immune functions, they are often categorized in additional ways, based on their roles in innate immunity, adaptive immunity, cell-mediated immunity, humoral immunity, etc.

Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.