Ceruloplasmin
Fasting Required: No

Specimen: Blood, frozen

Results: 5-7 Business Days

Description:
Ceruloplasmin is the major copper-carrying protein in the blood, and plays a role in iron metabolism. Copper is an essential mineral that is absorbed in the intestines and then transported to the liver, where it is stored or used to produce a variety of enzymes. About 95% of the copper in the blood is bound to ceruloplasmin. Decreased levels of ceruloplasmin are found in Wilson's Disease, fulminant liver failure, intestinal malabsorption, renal failure resulting in proteinuria, chronic active hepatitis and malnutrition. Elevated levels are found in primary biliary cirrhosis, pregnancy (first trimester), oral contraceptive use and in acute inflammatory conditions since ceruloplasmin is an acute phase reactant.

Methodology:
Nephelometry

Limitations:
Since ceruloplasmin is an acute phase reactant, caution is necessary when inflammation or infection are present.

Alternative Name(s):
Wilson's Disease, Copper Oxide

Note: Result turn around times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.