DUTCH Cycle Mapping Plus-Precision Analytical Inc Test Kit

Note: This is a home collection test kit that will be mailed to you.

Fasting Required: No

Specimen: 25 dried urine samples taken directly upon waking; 6 saliva samples

Lab: Precision Analytical

Results: 10-14 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Patient Instructions: This test will take a great deal of time as you will be collecting a series of samples throughout the course of one menstrual cycle.

Please read the collection instructions thoroughly prior to starting; for additional assistance, please watch the Cycle Mapping Collection video www.dutchtest.com/videos/sample-collection.

This test is intended for women with cycling ovaries who are menstruating OR women who are not menstruating because they have had a partial hysterectomy (ovaries intact) or ablation.

This test is not intended for women who are not cycling, on hormonal birth control, hormone replacement therapy or are post-menopausal, unless otherwise instructed by your healthcare practitioner.

**If you are taking hormone therapy, specifically estrogens, progesterone or pregnenolone, it is typically required to stop for the collection period. Do not stop any prescription hormones unless instructed by your provider. Oral estrogen, progesterone, or pregnenolone taken during the collection schedule will produce high levels of hormone metabolites measured that will not correlate with blood levels. This increase lasts for up to 48-72 hours after taking the hormone. If you are taking oral estrogen, progesterone or pregnenolone, please contact your healthcare practitioner before taking this test.

Results:For some women, testing reproductive hormones (progesterone, estrogen, etc.) on a single day is sufficient. In other scenarios, the clinical picture cannot be properly captured without “mapping” out the hormonal pattern throughout their menstrual cycle. The expected pattern of hormones shows relatively low estrogen levels early in the cycle, a surge around ovulation and modest levels in the latter third of the cycle (the luteal phase). Progesterone levels, on the other hand, stay relatively low until after ovulation. After ovulation levels ideally increase (>10-fold) and then drop back down at the end of the cycle. A disruption in this cycle can lead to infertility or hormonal imbalance.

The DUTCH Cycle Mapping maps the progesterone and estrogen pattern throughout the menstrual cycle. It provides the full picture of a woman's cycle to answer important questions for patients with month-long symptoms, infertility and PCOS.

Analytes tested:
Estradiol (9)
Estrone (9)
a-Pregnanediol (9)
b-Pregnanediol (9)
b-Pg / E2 Ratio
Cortisol Awakening Response