Anti-dsDNA Antibodies
Fasting Required: No

Specimen: Blood

Lab: Quest Diagnostics

Results: 1-3 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Description: Present in 80% to 90% of SLE cases. High levels of anti-dsDNA is strongly associated with lupus and is often significantly increased during or just prior to a flare-up. Anti-dsDNA is sometimes present with diseases such as chronic hepatitis, primary biliary cirrhosis, infectious mononucleosis, and Mixed Connective Tissue Disease.

Clinical Significance: dsDNA Antibody is detected in patients with active systemic lupus erythematosus (SLE) and approximately 20% of patients with Mixed Connective Tissue Disease.

Alternative Name(s): dsDNA, Double-Stranded DNA Antibody, Native DNA, Anti-DNA, (dsDNA)