Porphyrins Profile, Urine-Genova Kit

Note: This is a home collection test kit that will be mailed to you.



Fasting Required: No

Specimen: Urine

Results: 7-10 Business Days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Special Instructions: It is not necessary to discontinue nutritional supplements prior to this specimen collection. Abnormalities that may be found will reveal special needs that have not been met by recent dietary and supplemental intake.
Decrease fluid intake to avoid excessive dilution of the urine:
- For adults, restrict intake to three 8 oz. glasses or less for 24 hours
- Make sure that no more than 8 oz. of this is consumed after 8:00 PM the evening prior to urine collection.
Do not collect urine during menstruation.
Please keep specimen out of excess light and heat. Storing specimen in the amber vial in the freezer or with an ice pack provides specimen stability. Vial contains preservative - Do Not Rinse

Description: The Porphyrins Profile can help identify the severity of heavy metal toxicity or organic chemical exposure in patients. Chemical exposure and a heavy toxic burden can have physiological effects resulting in impaired metabolism and cellular function.

Porphyrins are proteins involved in the formation of heme measured in urine. Heme is essential for the proper function of many proteins including oxygen transport, energy production, and detoxification. Proper porphyrin production is essential for our body's capacity to detoxify toxins.

Porphyrins are particularly well suited for assessing heavy metal toxicity. First, the heme pathway is a constantly-changing pathway that is active in almost every cell of the body. Any disturbance in the pathway tends to cause rapid and relatively large accumulations of intermediates, such as porphyrins. Second, the enzymes of the pathway are widely distributed in human tissues, and are highly sensitive to the presence of various toxins, creating the large accumulation of porphyrins in the pathway.

Analytes Tested:
Copro I/Copro III
Coproporphyrin I
Coproporphyrin III
Creatinine
Heptacarboxyporphyrin
Hexacarboxyporphyrin
Pentacarboxyporphyrin
Precopro/Uro I & III
Precoproporphyrin
Total Porphyrins
Uroporphyrin I & III