Alkaline Phosphatase, Serum
Fasting Required: Yes 10-12 hours

Specimen: Blood

Lab: Quest Diagnostics

Results: 2-3 business days

Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Description: Alkaline phosphatase (ALP) is an enzyme mostly produced in your liver, but is also made in your bones, intestines, and kidneys. In pregnant women, ALP is made in the placenta.. ALP helps break down proteins in the body and exists in different forms, depending on where it originates.

Higher-than-normal levels of ALP may indicate hepatitis, cirrhosis (scarring) of the liver, liver cancer, gallstones, or a blockage in your bile ducts. High levels may also indicate an issue related to the bones such as rickets, Paget’s disease, bone cancer, or an overactive parathyroid gland. In rarer cases, high ALP levels can indicate heart failure, kidney cancer, mononucleosis, or a blood infection. Moderate elevations of alkaline phosphatase may be seen in several conditions that do not involve the liver or bone. Among these are Hodgkin's disease, congestive heart failure, ulcerative colitis, regional enteritis, and intra-abdominal bacterial infections. Elevations are also observed during the third trimester of pregnancy. Having lower-than-normal ALP levels is rare, but can indicate malnutrition or a deficiency in vitamins and minerals.