Cardiolipin Antibodies (IgA, IgG, IgM)
Fasting Required: No

Specimen: Blood

Lab: Quest Diagnostics

Results: 3-5 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Description: Detects the presence of three classes (IgG, IgM, and/or IgA) of cardiolipin antibodies. The antibodies are produced by the immune system in response to a perceived threat and can affect the body's ability to regulate blood clotting in a way that is not well understood. These proteins are the most common form of antiphospholipid antibodies, a group of autoantibodies associated with excessive clotting and autoimmune diseases, such as Systemic Lupus Erythematosus (SLE). They may also be detected temporarily in people with acute infections, HIV/AIDS, some cancers, with drug treatments (such as phenytoin, penicillin, and procainamide), and in the elderly.

Elevations of cardiolipin antibodies have been seen in idiopathic thrombocytopenic purpura, rheumatoid and psoriatic arthritis, low platelet count (thrombocytopenia), recurrent miscarriages (especially in the second and third trimester), with premature labor, preeclampsia and primary Sjögren's syndrome.